Tina Fey's hit comedy 30 Rock will come to an end after one more season.
The series has been a critical smash since it first aired in 2006, and has won a string of Emmys and Golden Globe awards.
It was reported Fey's co-star Alec Baldwin was leaving the hit show earlier this year, but bosses at NBC have confirmed the main cast will all return for a seventh and final run.
The move comes amid falling ratings for the show, which has attracted star cameos from Oprah Winfrey, Jennifer Aniston, Susan Sarandon, Matt Damon and environment campaigner Al Gore.
When asked by a fan on Twitter.com what he felt about the show's end, Baldwin replied: "The time is nigh."
NBC bosses will also axe the network's other comedies Community and Parks and Recreation after one more season to make way for new projects.