The toys and the "Grown Ups" ruled the box office, combining to make $100 million over the weekend.
Adam Sandler's comedy opened with $41 million but failed to steal the top spot from "Toy Story 3," which raked in $59 million in its second week on release.
Tom Cruise and Cameron Diaz's action comedy Knight and Day opened in third place with a distant and disappointing $20.5 million - the worst opening for a Cruise film in 20 years.
"The Karate Kid" and "The A-Team" round out the new top five.
See more "Knight And Day" photos here!