Film actors Dermot Mulroney and Emily Watson have been cast in the highly anticipated Lifetime Original Movie event, "The Memory Keeper's Daughter," based on Kim Edwards' best-selling, critically acclaimed novel of the same name.

Named by USA Today as its "Book of the Year" for 2006, the novel has 5 million copies in print and has spent over 60 weeks on The New York Times Best Seller list, holding the number-one spot for seven weeks. Production begins this November, with DGA Award-winning and Emmy nominated director Mick Jackson set to direct. "The Memory Keeper's Daughter" will premiere in March 2008 on Lifetime Television.

In "The Memory Keeper's Daughter," a secret shapes the lives of two families over a quarter of a century, beginning in 1964. During a paralyzing winter storm, Dr. David Henry (Mulroney) is forced to deliver his own twin babies. With his wife Norah under heavy sedation, he welcomes a healthy son, Paul, and a daughter, Phoebe, who has Down syndrome. Hoping to spare his wife any heartache for having to care for a special needs child, David tells Norah their daughter died at birth and orders the nurse, Caroline (Watson), to place Phoebe in an institution. However, unable to abandon the newborn, the nurse secretly decides to raise Phoebe as her own in another city.

As years pass, the two families' lives are in stark contrast to each other. David's overwhelming guilt surrounding his deception shatters the Henry's marriage and Norah mourns the loss of their child. Meanwhile, Caroline's relationship with Phoebe becomes the most rewarding and fulfilling experience of her life.