Five actors have been cast in season four of the Emmy Award-winning series House, which premieres Tuesday, Sept. 25 (9:00-10:00 PM ET/PT) on FOX.

Olivia Wilde (“The Black Donnellys,” “The O.C.”), Kal Penn ("24," “The Namesake,” “Harold & Kumar Go To White Castle”), Peter Jacobson (“The Starter Wife,” “Law & Order”), Anne Dudek (“Big Day”) and Edi Gathegi (“Lincoln Heights,” “Gone Baby Gone”) play candidates for a fellowship opportunity with Dr. House. The actors have been cast for an undetermined number of episodes.