The former (and forever) Spider-Man is set to star in and produce the screen adaptation of Robert C. O'Brien's acclaimed science fiction novel, "Z For Zachariah," according to Variety. 

"Z For Zachariah" follows a Midwestern teenager who lives alone and maintains a farm in the only valley with breathable air (thanks to a the area's self-contained weather system) in the wake of a nuclear war. Her solitude — and safety — is threatened when two strangers arrive from the forest, with Maguire set to play a mysterious scientist whom the girl nurses back to health after he falls ill from a contaminated stream.

"Z For Zachariah" will be directed by Craig Zobel, whose controversial drama, "Compliance," opens on Aug. 17. The book, originally published in 1974, was adapted by Nissar Modi, who recently penned "Outback" for "Hunger Games" director Gary Ross.