Mike Tyson, in his first role following his memorable cameo in the hit film "The Hangover," is confirmed to appear as a guest star on the new half-hour comedy series Brothers, which debuts with a special one-hour series premiere on Friday, September 25 at 8:00 PM ET/PT on Fox. In an upcoming episode, Tyson shows up to collect money from MIKE (Michael Strahan) at his brother's (Daryl Chill Mitchell) restaurant.

Brothers is a sitcom in which Michael Strahan ("FOX NFL Sunday") plays a former NFL star dealing with post-gridiron life as he moves back home with his family, co-starring Daryl Chill Mitchell ("Ed," "Veronica's Closet"), CCH Pounder ("The Shield") and Carl Weathers ("Rocky").

Check out more on BROTHERS Here.

Retired NFL star Mike Trainor (Michael Strahan, second from R) returns to his hometown to rebuild his relationship with his family in the new FOX comedy BROTHERS © Fox Broadcasting Co.