The actor said that Tinseltown is "run by Jews" and said Hollywood unfairly treated Mel Gibson, who made anti-semitic remarks after being arrested by a Jewish police officer in 2006.
Among other things he said: "The policeman who arrested him has never used the word n**ga or that f**king Jew? I'm being brutally honest here. It's the hypocrisy of it that drives me crazy... Mel Gibson is in a town that's run by Jews and he said the wrong thing because he's actually bitten the hand that I guess has fed him - and doesn't need to feed him anymore because he's got enough dough."
In response to Oldman's remarks, Anti-Defamation League director Abraham H. Foxman said in a statement: "Mel Gibson's ostracization in Hollywood was not a matter of being 'politically incorrect', as Mr. Oldman suggests, but of paying the consequences for outing himself as a bigot and a hater. It is disturbing that Mr. Oldman appears to have bought into Mr. Gibson's warped and prejudiced world view."
Many others were also offended by the interview, forcing Oldman to issue a statement to the Anti-Defamation League.
"I am deeply remorseful that comments I recently made in the Playboy interview were offensive to many Jewish people," he wrote.
"Upon reading my comments in print - I see how insensitive they may be, and how they may indeed contribute to the furtherance of a false stereotype. Anything that contributes to this stereotype is unacceptable, including my own words on the matter.
"I hope you will know that this apology is heartfelt, genuine, and that I have an enormous personal affinity for the Jewish people in general, and those specifically in my life. The Jewish people, persecuted thorough the ages, are the first to hear God's voice, and surely are the chosen people.
"I would like to sign off with 'Shalom Aleichem' - but under the circumstances, perhaps today I lose the right to use that phrase, so I will wish you all peace."
Oldman stars in the upcoming film "Dawn of the Planet of the Apes," which hits theaters July 11.