Director Steven Soderbergh's star-studded disaster movie "Contagion" has topped the box office.
The film, about a deadly virus, opened with $23.1 million over the weekend.
Summer sleeper hit "The Help" dropped to second after spending three weeks at the top.
Mixed martial arts movie "Warrior" opened with $5.6 million. "The Debt" and "Colombiana" round out the new top five.