Christina Applegate is no longer interested in staying "Up All Night." The actress is quitting the NBC sitcom and made the announcement official on Friday by releasing a statement to Deadline.com.
 
She wrote, "It's been a great experience working on Up All Night, but the show has taken a different creative direction and I decided it was best for me to move on to other endeavors. I will miss the cast, producers and crew, and wish them the best always."
 
Reports indicate that Applegate's departure is linked to the show's plans to switch from a single-camera format to multi-camera filming and begin taping in front of a live studio audience.
 
The show also stars Maya Rudolph and Will Arnett. Applegate plays Reagan, a successful public relations executive, and Arnett plays Chris, her stay-at-home husband. The two have just become parents – a surprise that has set their lives on a new path as responsible adults.