You Me And Dupree Cast and Crew
 Owen Wilson - (Randolph Dupree) |
 Kate Hudson - (Molly Peterson) |
 Matt Dillon - (Carl Peterson) |
 Seth Rogen - (Neil) |
 Amanda Detmer - (Annie) |
 Todd Stashwick - (Rod) |
 Michael Douglas - (Mr Thompson) |
 Ralph Ting - (Toshi) |
 Harry Dean Stanton - (Curly) |
 Bill Hader - (Mark) |
 Lance Armstrong - (Himself) |
| Jason Winer - (Eddie) |
| Sidney Liufau - (Paco) |
 Billy Gardell - (Bartender Dave) |
| Elizabeth Vargas - (Aaron) |
| Houston McCrillis - (Dougie) |
| Bob Larkin - (Army Veteran) |
| Suzanne Ford - (Margaret) |
| Fenessa Pineda - (Lucita) |
 Tasha Smith - (Co-Worker) |
| John Ruby - (Spin Instructor) |
| Claudia Choi - (Pam) |
 Summer Altice - (Blonde Woman) |
| Jeanine Hass - (Blonde Woman) |
| Peter Ruocco - (Wedding Planner) |
| Lance Irwin - (Boy's Father) |
| Mario Quinonez, Jr. - (Little Dupree) |
| Mario Quinonez, Jr. - (2nd Grader) |
| Jay Lembeck - (Minister) |
| Gil Harris - (Reese) |
| Pat Crawford Brown - (Aunt Kathy) |
| Bayani Ison - (Hawaiian Bartender) |
| Joelle Wilson - (Uncle Joe) |
| Howard S. Lefstein - (Dupree Body Double) |
| Blaine Pate - (Party Guest) |
| Kevin Breznahan - (Party Guest) |
| Trevor Stock - (Party Guest) |
| Sean Perrone - (Party Guest) |
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