The Babe Cast and Crew
 John Goodman - (George Herman "Babe" Ruth) |
 Kelly McGillis - (Claire Hodgeson-Ruth) |
 Trini Alvarado - (Helen Woodford-Ruth) |
 Bruce Boxleitner - (Jumpin' Joe Dugan) |
| Peter Donat - (Harry Frazee) |
 James Cromwell - (Brother Mathias) |
| J.C. Quinn - (Jack Dunn) |
| Bernard Kates - (Colonel Jacob Ruppert) |
| Michael McGrady - (Lou Gehrig) |
| Stephen Caffrey - (Johnny Sylvester, age 30) |
| James Andelin - (Asa) |
| Larry Cedar - (Forbes Field Announcer) |
| Ron Dean - (Umpire Owens) |
| James Deuter - (Society Man) |
| Matt Doherty - (Boy in Car) |
| James "Ike" Eichling - (Cigar Smoker) |
| Ralph Foody - (Pittsburgh Man) |
| Brett Hadley - (1st Umpire) |
 Irma P. Hall - (Fanny Baily) |
| Harry Hutchinson - (Tris Speaker) |
| Roy Hytower - (Elevator Operator) |
| Beep Iams - (Boy at St. Mary's) |
| Ken Kells - (2nd Umpire) |
| Dana Lubotsky - (Julia) |
| Ralph Marrero - (Francesco Stephano "Ping Bodie" Pezzolo) |
| Jim Ortlieb - (Scribe) |
| Michael Papajohn - (Heckler) |
| Rick Reardon - (Ernie Shore) |
| Hank Robinson - (4th Umpire) |
| Gene Ross - (Brother Paul) |
| Ned Schmidtke - (Hospital Reporter) |
| Peter Siragusa - (Umpire Hildebrand) |
| Richard Tyson - (Guy Bush) |
| Ron West - (Spectator) |
| Laura Whyte - (Mrs. Ballister) |
| Jeffrey Wiseman - (Boy at St. Mary's) |
| Alan Johnson - (Orphanage Reporter) |
| William J. Norris - (Fedoras) |
| Shannon Cochran - (Flapper) |
| Danny Goldring - (Carrigan) |
| Shirley Spiegler-Jacobs - (Woman in Coffee Shop) |
| Michael Krawic - (Theatergoer) |
| Bob Swan - (George Ruth Sr.) |
| Meg Thalken - (Johnny's Nurse) |
| Steve King - (Fuchs) |
| Michael Nicolosi - (Jimmy Colosimmo) |
| W. Earl Brown - (Herb Pennock) |
| Nicholas Rudall - (Brother Malcolm) |
| Albert B. Smith - (Speakeasy Band) |
| Daniel Anderson - (Bistro Band) |
| John Webb - (Eddie) |
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