Step Brothers Cast and Crew
 Will Ferrell - (Brennan Huff) |
 John C. Reilly - (Dale Doback) |
 Mary Steenburgen - (Nancy Huff) |
 Richard Jenkins - (Dr. Robert Doback) |
 Adam Scott - (Derek) |
 Kathryn Hahn - (Alice) |
 Andrea Savage - (Denise) |
| Lurie Poston - (Tommy) |
| Elizabeth Yozamp - (Tiffany) |
| Logan Manus - (Chris Gardoki) |
| Travis Flory - (Redheaded Kid) |
| Lili McKay - (7-year-old girl) |
| Shira Piven - (Nurse) |
| Seth Morris - (Doctor) |
| Wayne Federman - (Blind Man) |
| Maria Quiban - (TV Anchor) |
| Danielle Schneider - (Receptionist) |
| Gillian Vigman - (Pam Gringe) |
| Brian Huskey - (Interviewer) |
 Seth Rogen - (Sporting Goods Manager) |
| Brian Henchy - (Interviewer) |
 Chris Henchy - (First homebuyer) |
| Mary Catherine Hamelin - (First homebuyer) |
| Ian Roberts - (Male Therapist) |
| Erica Vittana Phillips - (Second homebuyer) |
 Phil LaMarr - (second homebuyer) |
 Rob Riggle - (Randy) |
| Jason Davis - (TJ) |
| Paula Killen - (Rental Agent) |
 Ken Jeong - (Employment Agent) |
 Horatio Sanz - (Lead Singer) |
| Kyle Felts - (Wine Mixer Heckler) |
| Jake Szymanski - (Caterer) |
 Matt Walsh - (Drunk Corporate Guy) |
| Dmitri Schuyler-Linch - (6-year-old Derek) |
| Bryce Hurless - (9-year-old Brennan) |
| Brent White - (Therapy Patient) |
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