Melinda and Melinda Cast and Crew
 Radha Mitchell - (Melinda) |
 Chloë Sevigny - (Laurel) |
 Jonny Lee Miller - (Lee) |
 Will Ferrell - (Hobie) |
 Amanda Peet - (Susan) |
 Chiwetel Ejiofor - (Ellis) |
 Wallace Shawn - (Sy) |
 Josh Brolin - (Greg) |
 Gene Saks |
 Vinessa Shaw - (Stacey) |
 Steve Carell - (Walt) |
| Geoffrey Nauffts - (Bud) |
| Neil Pepe - (Al) |
| Larry Pine - (Max) |
| Matt Servitto - (Jack) |
 Brooke Smith - (Cassie) |
 Arija Bareikis - (Sally) |
 Shalom Harlow - (Joan) |
| Zak Orth - (Peter) |
| Christina Kirk - (Jennifer) |
| Andy Borowitz - (Doug) |
| David Aaron Baker - (Steve) |
| Stephanie Roth Haberle - (Louise) |
| Katie Kreisler - (Director) |
 Daniel Sunjata - (Billy) |
| Rob Buntzen - (Antique Shop Owner) |
| Michael J. Farina - (Man With Dog) |
| Alyssa Pridham - (Acting Student) |
| Quincy Rose - (2nd A.D.) |
| Rick Vincent Holmes - (Party Guest) |
| Michele Durning - (Party Guest) |
| Yi-Wen Jiang - (Shanghai Quartet) |
| Honggang Li - (Shanghai Quartet) |
| Weigang Li - (Shanghai Quartet) |
| Nicholas Tzavaras - (Shanghai Quartet) |
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