Duplex Cast and Crew
 Ben Stiller - (Alex Rose) |
 Drew Barrymore - (Nancy Kendricks) |
 Eileen Essell - (Mrs. Connelly) |
 Harvey Fierstein - (Kenneth) |
 Robert Wisdom - (Officer Dan) |
 Justin Theroux - (Coop) |
 Amber Valletta - (Celine) |
 James Remar - (Chick) |
 Swoosie Kurtz - (Jean) |
| Joe Banks - (Police Officer) |
| Edward Edwards - (Antique Dealer) |
| Louis Giambalvo - (Pharmacist) |
| Jenette Goldstein - (Moderator) |
| Philip Perlman - (Phil) |
 Wallace Shawn - (Herman) |
| Tracey Walter - (Pharmacy Customer) |
 Chris Mulkey |
| Linda Porter - (Old Biddy #2) |
| Stomy Bugsy - (Little Dick) |
| Christina Kirk - (Mrs. Friedman) |
| John Hamburg - (Mr. Friedman) |
 Mía Maestro - (Little Dick) |
| Christopher Doyle - (Tavern Bartender) |
| Chuma Hunter-Gault - (Mailroom Guy) |
 Maya Rudolph - (Tara) |
| Claude Picasso - (Little Dick) |
| Sherry Klein |
| Kumar Pallana - (Indian Restaurant Owner) |
 Michelle Krusiec - (Dr. Kang) |
 Geraldine Hughes - (Receptionist) |
| Leyna Nguyen - (Female Newscaster) |
| Jackie Titone - (Bartender) |
| Tim Maculan - (Terrence) |
| Eugene Lazarev - (Mr. Dzerzhinsky) |
| Cheryl Klein - (Ginger) |
| Gary Riotto - (Drug Dealer) |
| Margie Loomis - (Old Biddy #1) |
| Jim Castillo - (Weatherman) |
| Michael Fahn - (Sneezer on Train) |
| Roberta R. Deen - (Caterer) |
| Christine La Fontaine - (Don Piper Fan #1) |
| Guiles - (Little Dick) |
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