The Core Cast and Crew
 Aaron Eckhart - (Dr. Josh Keyes) |
 Hilary Swank - (Major Rebecca "Beck" Childs) |
 Delroy Lindo - (Dr. Ed "Braz" Brazzelton) |
 Stanley Tucci - (Dr. Conrad Zimsky) |
 D.J. Qualls - (Rat) |
 Richard Jenkins - (General Purcell) |
 Tchéky Karyo - (Dr. Serge Levesque) |
 Bruce Greenwood - (Commander Richard Iverson) |
 Alfre Woodard - (NASA Chief Talma Stickley) |
| Nathaniel de Veaux - (U.S.S. Constellation Captain) |
 Glenn Morshower - (FBI Agent) |
| John Shaw - (FBI Agent, Rat's Apartment) |
| Claire Riley - (News Anchor) |
| Gregg Bennett - (Technician, Virgil Base) |
| Rosa DiBrigida - (Rome Café Patron) |
| Matt Winston - (Luke Barry) |
| Lenie Scoffie - (Paris Café Lady) |
| Laurie Murdoch - (Project Destiny Engineer) |
| Christopher Shyer - (Dave Perry) |
| Anthony Harrison - (FBI Agent) |
| Ray Galletti - (Paul) |
| Fred Keating - (Court Martial Presiding Officer) |
| Hrothgar Matthews - (Chief Engineer, Mission Control) |
| Dion Johnstone - (Flight Engineer Timmins) |
| Bart Anderson - (Dad) |
 Rekha Sharma - (Danni) |
| Nicole Leroux - (Mom) |
| Fred Ewanuick - (Endeavor Flight Engineer) |
| Nickolas Baric - (Security Policeman, Tribunal) |
| Eileen Pedde - (Lynne) |
| Marke Driesschen - (News Anchor) |
| Costa Spanos - (Project Destiny Engineer) |
| Tom Schilte - (Acker) |
| Justin Callan - (Little Boy) |
| Chris Humphreys - (GBTV Reporter, Trafalgar Square) |
| Shawn Green - (Himself) |
| Hong Ming-Tzong - (Scientist) |
| Jennifer Spence - (Zimsky's Assistant) |
| Michael St. John Smith - (Pentagon General) |
| Roberto Roberto - (Rome Café Patron) |
| Ermanno De Biagi - (Rome Café Patron) |
| Marcello Laurentis - (Rome Café Patron) |
| Monique Martel - (Paris Café Lady) |
| Robert Mantiopyes - (U.S.S. Constellation Screen Ops) |
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