It begins in a flash, as one man is instantaneously struck blind while driving home from work, his whole world suddenly turned to an eerie, milky haze. One by one, each person he encounters--his wife, his doctor, even the seemingly good Samaritan who gives him a lift home--will in due course suffer the same unsettling fate. As the contagion spreads, and panic and paranoia set in across the city, the newly blind victims of the "White Sickness" are rounded up and quarantined within a crumbling, abandoned mental asylum, where all semblance of ordinary life begins to break down. But inside the quarantined hospital, there is one secret eyewitness: one woman who has not been affected but has pretended she is blind in order to stay beside her beloved husband. Armed with increasing courage and the will to survive, she will lead a makeshift family of seven people on a journey, through horror and love, depravity and beauty, warfare and wonder, to break out of the hospital and into the devastated city where they may be the only hope left.