Bio-Dome Cast and Crew
 Pauly Shore - (Bud Macintosh) |
 Stephen Baldwin - (Doyle Johnson) |
 William Atherton - (Dr. Noah Faulkner) |
 Joey Lauren Adams - (Monique) |
| Teresa Hill - (Jen) |
| Henry Gibson - (William Leaky) |
| Rodger Bumpass - (Narrator) |
 Denise Dowse - (Olivia Biggs) |
| Paul Eiding - (Assistant) |
 Kyle Gass - (Tenacious D) |
| Cecile Krevoy - (Woman in Bandstand) |
 Rose McGowan - (Denise) |
| Rene L. Moreno - (Partier) |
 Taylor Negron - (Russell) |
| Philip Proctor - (Axl) |
 Tucker Smallwood - (Gates) |
| Kevin West - (T C Romulous) |
 Jack Black - (Tenacious D) |
 Kylie Minogue - (Petra Von Kant) |
| Dara Tomanovich - (Mimi Simkins) |
| Jeremy Jordan - (Trent) |
| Mark Burton - (Guy) |
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