- Sabathia, C.C.
- Sadler, Elliott
- Safin, Marat
- Safina, Dinara
- Sakic, Joe
- Sale, Jamie
- Sampras, Pete
- Sanchez, Mark
- Sandberg, Ryne
- Sanders, Deion
- Sapp, Warren
- Sayers, Gale
- Schiavone, Francesca
- Schilling, Curt
- Schwikert, Tasha
- Scott, Bart
- Seau, Junior
- Selanne, Teemu
- Seles, Monica
- Seth Wescott
- Seymour, Richard
- Sharapova, Maria
- Sharper, Darren
- Sheamus
- Sheckler, Ryan
- Shockey, Jeremy
- Simms, Phil
- Simpson, O.J.
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- Slater, Kelly
- Smarty Jones
- Smith, Alex
- Smith, Emmitt
- Smith, Lovie
- Smith, Steve
- Smoltz, John
- Solo, Hope
- Soni, Rebecca
- Sorenstam, Annika
- Soriano, Alfonso
- Sosa, Sammy
- Sprem, Karolina
- Srebotnik, Katarina
- St-Pierre, Georges
- Stafford, Matthew
- Stenhouse Jr., Ricky
- Stewart, Tony
- Stone Cold Steve Austin
- Stoudemire, Amare
- Strahan, Michael
- Strawberry, Darryl
- Suarez, Luis
- Suh, Ndamukong
- Sullivan, Steve
- Summitt, Pat
- Sundin, Mats
- Suzuki, Ichiro
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