- Eads, George
- Ealy, Michael
- Easton, Michael
- Eastwood, Clint
- Eberl, Luke
- Ebert, Roger
- Ebsen, Buddy
- Eccleston, Christopher
- Eckhart, Aaron
- Eckhouse, James
- Eddy, Nelson
- Edmondson, Adrian
- Edner, Bobby
- Edwards, Anthony
- Edwards, Blake
- Edwards, Sam
- Efron, Zac
- Egoyan, Atom
- Ehrlich, Max
- Eigeman, Chris
- Eigenberg, David
- Eisenberg, Aron
- Eisenberg, Jesse
- Eisner, Breck
- Eisner, Michael
- Ejiofor, Chiwetel
- Elam, Jack
- Elba, Idris
- Eldard, Ron
- Elfman, Bodhi
- Elizondo, Hector
- Elliot, David James
- Elliott, Chris
- Elliott, Denholm
- Elliott, Sam
- Ellsworth, Kiko
- Elman, Jamie
- Elphick, Michael
| - Elton, Ben
- Elwes, Cary
- Ely, Ron
- Embry, Ethan
- Emerson, Michael
- Emmerich, Noah
- Emmerich, Roland
- England, Hal
- Englund, Robert
- Enos, John
- Eplin, Tom
- Epps, Mike
- Epps, Omar
- Erez, Sigal
- Ericson, John
- Eriksen, Kaj-Erik
- Eriksson, Josh
- Ermey, R. Lee
- Erwin, Bill
- Erwin, Mike
- Escarpeta, Arlen
- Esposito, Giancarlo
- Estelle, Don
- Estes, Rob
- Estes, Will
- Estevez, Emilio
- Estevez, Joe
- Estrada, Erik
- Etebari, Eric
- Eubanks, Bob
- Evans, Chris
- Evans, Josh Ryan
- Evans, Lee
- Evans, Rashad
- Evans, Troy
- Everett, Rupert
- Evigan, Greg
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