2. Four Minutes--Madonna (ft. Justin Timberlake) (2008)

One of the many duets that Timberlake has performed in the past several years, nothing compared to this war of words with Madonna. Said Madonna about working with JT, "Writing together with somebody is very intimate." In the end, Madonna was smoked by Timberlake and although it wasn't a huge hit here, it was a huge hit around the world, and charted at No. 1 in 21 countries

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